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Rabbit Polyclonal Antibody to PLAUR

CAT: 1725-P07548-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P07548-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Product Name Alternative
CD87; UPAR; URKR; U-PAR
Swiss Prot
Q03405
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human PLAUR
Clonality
Polyclonal
Applications
WB, IHC
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
PLAUR
Bands Size
37 kDa

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