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Phospho-BACE1 (Ser498) Rabbit Polyclonal Antibody

CAT: 0013-GTR17705835-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0013-GTR17705835-01Size:50 μL
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Description
Phospho-BACE1 (Ser498) Rabbit Polyclonal Antibody
Product Name Alternative
ASP2; BACE; HSPC104; BACE1_HUMAN; BACE1; Aspartyl protease 2 (ASP2 | Asp 2) ; Beta-site amyloid precursor protein cleaving enzyme 1 (Beta-site APP cleaving enzyme 1) ; Memapsin-2; Membrane-associated aspartic protease 2; 3.4.23.46; KIAA1149; BACE1_MOUSE; BACE1_RAT; beta-secretase 1; beta-site APP-cleaving enzyme; beta-site APP-cleaving enzyme 1; memapsin 2; aspartyl protease 2; BACE1 (phospho-S498) ; p-BACE1; phospho-BACE1; BACE1 (phospho-Ser498)
UniProt
P56817
Reactivity
Human, Mouse, Rat
Immunogen
KLH conjugated Synthesised phosphopeptide derived from human BACE1 around the phosphorylation site of Ser498 DI (p-S) LL
Target
BACE1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Affinity purified by Protein A
Concentration
1mg/ml
Dilution
IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500
Form
Liquid
Molecular Weight
51 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Prediction Reactivity
Bovine, Canine, Equine, Gallus, Porcine, Rabbit
Tested Applications
IF, IHC-Fr, IHC-P
Host or Source
Rabbit
Preservative
0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
Isotype
IgG

UniProtKB · P56817

Beta-secretase 1

BACE1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P56817
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BACE1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.23.46
Processing
Precursor
Secondary accessions
A0M8W7, B0YIU9, E9PE65, H7BXJ9, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5, Q9ULS1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugationZymogen

Coding sequence diversity

Alternative splicing

Molecular function

Aspartyl proteaseHydrolaseProtease

Cellular component

Cell membraneCell projectionCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusLysosomeMembrane

Domain

SignalTransmembraneTransmembrane helix

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