BIIL-260

CAT: 0804-HY-114641Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-114641Size:1 Each
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Description
BIIL-260 is a potent and long-acting orally active leukotriene B (4) receptor LTB4 antagonist, with anti-inflammatory activity. BIIL-260 interacts with the LTB4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with the Ki value of 1.7 nM[1].
CAS Number
[204974-93-6]
UNSPSC
12352005
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/biil-260.html
Smiles
N=C(N)C1=CC=C(C=C1)OCC2=CC=CC(COC3=CC=C(C=C3)C(C4=CC=C(C=C4)O)(C)C)=C2
Molecular Formula
C30H30N2O3
Molecular Weight
466.57
References & Citations
[1]Birke FW, et al. In vitro and in vivo pharmacological characterization of BIIL 284, a novel and potent leukotriene B (4) receptor antagonist. J Pharmacol Exp Ther. 2001 Apr;297 (1) :458-66.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
MBS5776536BIIL 260
MBS3846212-01BIIL-260 hydrochloride
A21788-10BIIL-260 hydrochloride 10mg
A21788-100BIIL-260 hydrochloride 100mg
A21788-5BIIL-260 hydrochloride 5mg
A21788-200BIIL-260 hydrochloride 200mg
A21788-1BIIL-260 hydrochloride 1mg
A21788-25BIIL-260 hydrochloride 25mg
A21788-50BIIL-260 hydrochloride 50mg
A21788-10mM-DBIIL-260 hydrochloride 10mM * 1mL in DMSO

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