RegisterLogin

Orcinol

CAT: 0804-HY-D0168-01Size: 500 mgDry Ice: NoHazardous: No
CAT#:0804-HY-D0168-01Size:500 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Orcinol (3,5-Dihydroxytoluene) is an organic compound used in biological dyeing and proteomics research. Orcinol inhibits melanogenesis in B16F10 cells by upregulating the MAPK/ERK signaling pathway, and suppresses the expression of MITF, tyrosinase (TYR), TRP1, and DCT. Orcinol exhibits certain DPPH radical scavenging activity. In addition, Orcinol can alter nitrogen balance in animals. Orcinol holds promise for research in cancer and metabolic diseases[1][2][3].
CAS Number
[504-15-4]
Product Name Alternative
3,5-Dihydroxytoluene
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
ERK; Fluorescent Dye; p38 MAPK; Tyrosinase
Type
Dye Reagents
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease; Others; Stem Cell/Wnt
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/orcinol.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC(C)=CC(O)=C1
Molecular Formula
C7H8O2
Molecular Weight
124.14
Precautions
H302, H315, H319, H335
References & Citations
[1]Murakami Y, et al. The Radical Scavenging Activity and Cytotoxicity of Resveratrol, Orcinol and 4-Allylphenol and their Inhibitory Effects on Cox-2 Gene Expression and Nf-κb Activation in RAW264.7 Cells Stimulated with Porphyromonas gingivalis-fimbriae. In Vivo. 2015 May-Jun;29 (3) :341-9.|[2]Yu C L, et al. Orcinol inhibits melanogenesis in B16F10 cells via the upregulation of the MAPK/ERK signaling pathway[J]. Natural Product Communications, 2023, 18 (3) : 1934578X231156704.|[3]Edwards MJ, et al. Acid loads induced by the detoxification of plant secondary metabolites do not limit feeding by common brushtail possums (Trichosurus vulpecula) . J Comp Physiol B. 2010 Feb;180 (2) :247-57.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Isoform
COX-2

Related Products

CatalogName
HY-N14544Orchinol

Alternative Products

CatalogName
C14173Orcinol
461606-01Orcinol Glucoside
AB3443Orcinol gentiobioside
GE8094-25gOrcinol anhydrous
GT3752-100gOrcinol monohydrate
MBS5790284beta-Orcinol

Popular Products