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YT117R

CAT: 0804-HY-169148Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-169148Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YT117R is a PROTAC degrader of FKBP12 and Pink: Target protein ligand: ; Black: linker (HY-42776) ; Blue: E3 ligase ligand (HY-78695) ).
UNSPSC
12352005
Target
Epigenetic Reader Domain; FKBP; PROTACs
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics; Immunology/Inflammation; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/yt117r.html
Smiles
C=CC(N1C[C@@H]([C@@H]1C(NC2=CC=CC3=C2N=CC=C3)=O)C4=CC=C(C=C4)C(NCCOCCOCCOCCNC(C[C@@H]5N=C(C6=C(N7C(C)=NN=C57)SC(C)=C6C)C8=CC=C(C=C8)Cl)=O)=O)=O
Molecular Formula
C50H52ClN9O7S
Molecular Weight
958.52
References & Citations
[1]Tao Y, et al. Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1. J Am Chem Soc. 2022 Oct 12;144 (40) :18688-18699.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
FKBP12

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CatalogName
T200965-01YT117R

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