Sucralfate

CAT: 0804-HY-B0644-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0644-01Size:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sucralfate (Sucrose octasulfate-aluminum complex) is a potent and orally active gastroprotectant with no systemic effects. Sucralfate inhibits peptic activity and binds to negatively charged subepithelial proteins exposed during mucosal injury, forming a viscous layer that protects the vascular bed and proliferative zone. Sucralfate is used for prevention and research of several gastrointestinal diseases in vivo[1][2].
CAS Number
[54182-58-0]
Product Name Alternative
Sucrose octasulfate-aluminum complex
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/Sucralfate.html
Solubility
1M NaOH : 20 mg/mL (ultrasonic; adjust pH to 12 with 1M NaOH)
Smiles
[OSO3[Al2(OH5)]][C@H]([C@@H](C[OSO3[Al2(OH5)]])O1)[C@H](O[S]=O=O=O=[OH5]#[Al]#[Al])[C@]1(C[OSO3[Al2(OH5)]])O[C@@H]2[C@H](O[S]=O=O=O=[OH5]#[Al]#[Al])[C@H](O[S]=O=O=O=[OH5]#[Al]#[Al])[C@H](O[S]=O=O=O=[OH5]#[Al]#[Al])[C@@H](C[OSO3[Al2(OH5)]])O2
Molecular Formula
C12H14Al16O75S8
Molecular Weight
2046.42
Precautions
H302, H315, H319, H335
References & Citations
[1]Chaim FM, et al. Evaluation of the application of enemas containing sucralfate in tissue content of neutral and acid mucins in experimental model of diversion colitis. Acta Cir Bras. 2014 Sep;29 (9) :544-52.|[2]Tracy L Hill, et al. Effect of sucralfate on gastric permeability in an ex vivo model of stress-related mucosal disease in dogs. J Vet Intern Med. 2018 Mar;32 (2) :670-678.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
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