Fibrinogen (Bovine)
CAT:
804-HY-125864-01
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Fibrinogen (Bovine)
- CAS Number: 9001-32-5
- UNSPSC Description: Fibrinogen (Bovine) is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases[1][2][3].
- Target Antigen: Interleukin Related; NF-κB
- Type: Biochemical Assay Reagents
- Related Pathways: Immunology/Inflammation;NF-κB
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/fibrinogen-bovine.html
- Purity: 92.0
- Smiles: [Fibrinogen (Bovine)]
- References & Citations: [1]Brown JH, et al. The crystal structure of modified bovine fibrinogen. Proc Natl Acad Sci U S A. 2000;97(1):85-90.|[2]Tyagi N, et al.Fibrinogen induces endothelial cell permeability. Mol Cell Biochem. 2008 Jan;307(1-2):13-22.|[3]Guo M, et al. Fibrinogen regulates the expression of inflammatory chemokines through NF-kappaB activation of endothelial cells. Thromb Haemost. 2004;92(4):858-866.
- Shipping Conditions: Blue Ice
- Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported