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Isoxepac

CAT: 0804-HY-W050088-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W050088-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Isoxepac (HP 549) is an orally active non-steroidal anti-inflammatory agent. Isoxepac can inhibit Carrageenan paw oedema, adjuvant-induced polyarthritis, and prostaglandin synthesis. Isoxepac (200 mg) has an analgesic effect after meniscectomy with a low incidence of side effects. Isoxepac can be used in the research of inflammatory (rheumatoid arthritis) and pain-related diseases[1][2][3].
CAS Number
55453-87-7
Product Name Alternative
HP 549
UNSPSC
12352005
Hazard Statement
H301
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/isoxepac.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)CC1=CC=C(C2=C1)OCC3=CC=CC=C3C2=O
Molecular Formula
C16H12O4
Molecular Weight
268.27
Precautions
H301
References & Citations
[1]L S Gerlis, et al. Isoxepac in rheumatoid arthritis: a double-blind comparison with aspirin. Rheumatol Rehabil. 1981 Feb 1;20 (1) :50-3.|[2]W J Honig, et al. Analgesic effect of isoxepac on postmeniscectomy pain: a controlled trial. J Clin Pharmacol. Feb-Mar 1982;22 (2-3) :82-8.|[3]H P Illing, et al. Species differences in the disposition and metabolism of 6,11-dihydro-11-oxodibenz[be]oxepin-2-acetic acid (isoxepac) in rat, rabbit, dog, rhesus monkey, and man. Drug Metab Dispos. Sep-Oct 1978;6 (5) :510-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1

Alternative Products

CatalogName
TRC-I917700-100MGIsoxepac
TRC-D288085-500MG2-Decarboxymethyl-2-carboxy Isoxepac

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