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HypoGel® 200 PHB

CAT: 0927-SP200110150130.25GSize: 25 gDry Ice: NoHazardous: No
CAT#:0927-SP200110150130.25GSize:25 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HypoGel® is a hydrophilic Gel® type resin which combines high capacities with good solvent compatibility. Glycol spacers with n = 5 or 10 EO units separate the reactive sites from the polystyrene matrix and modify the hydrophobic properties of the polystyrene backbone. Due to the spacer effect the functional group shows a higher mobility which results in higher kinetic rates and high resolution NMR spectra from immobilized compounds on the bead. The resin is compatible to a wide range of solvents and in contrast to polystyrene even polar solvents like methanol or ethanol can be used. These resins show high loading and a hydrophilicity between polystyrene and TentaGel®. This resin is recommended for the synthesis of short peptides (10 - 15 residues) . The p-hydroxybenzyl alcohol attached to HypoGel® makes this resin ideal for attaching carboxylic acids for further functionalisation and peptide synthesis. Cleavage conditions are concentrated TFA or TFA/DCM mixtures to provide carboxylic acids, peptides or cyclization-cleavage under acidic or basic conditions. In this resin the glycol spacer contains 5 EO units which separate the reactive sites from the polystyrene matrix.
Specifications
110 - 150 µm
Capacity
0.6 - 0.9 mmol/g

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