γ-Hexalactone

• Description:

  γ-Hexalactone is a gamma-lactone found in ripe fruits. γ-Hexalactone induces DNA damage and acts a substrate of paraoxonase 1 (PON1) [1][2][3].

• Product Name Alternative:

  γ-Caprolactone

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/gamma-hexalactone.html

• Purity:

  99.77

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C1OC(CC)CC1

• Molecular Formula:

  C6H10O2

• Molecular Weight:

  114.14

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [3]Shangula S, et al. PON1 increases cellular DNA damage by lactone substrates. Arch Toxicol. 2019 Jul;93 (7) :2035-2043.|[1]E-Nose and GC-MS Reveal a Difference in the Volatile Profiles of White- and Red-Fleshed Peach Fruit. Sensors (Basel) . 2018 Mar 2;18 (3) .|[2]Bianchi T, et al. Investigation of the aroma of commercial peach (Prunus persica L. Batsch) types by Proton Transfer Reaction-Mass Spectrometry (PTR-MS) and sensory analysis. Food Res Int. 2017 Sep;99 (Pt 1) :133-146.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [695-06-7]