A8 peptide

CAT: 0931-TP3968-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TP3968-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1140483-17-5
Target
HSP
Related Pathways
Cytoskeletal Signaling|||Metabolism
Bioactivity
A8 peptide is an Hsp72 antagonist that hinders tumor progression and metastasis by disrupting the Hsp72-TLR2 interaction and subsequent activation of MDSCs, thereby increasing cancer cells' sensitivity to chemotherapeutic agents like cisplatin (Cisplatin-induced apoptosis sensitivity) . A8 peptide is applicable in cancer research.
Smiles
C([C@@H](C(=O)N1[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(O)=O)=O)[C@@H](C)O)=O)CCC2)CCCNC(=N)N)=O)CCC1)NC(=O)[C@H]4N(C([C@H](CO)N)=O)CCC4)C=5C=6C(NC5)=CC=CC6
Molecular Formula
C48H66N12O12
Molecular Weight
1003.11
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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