A8 peptide

• Target :

  HSP

• Related Pathways :

  Cytoskeletal Signaling|||Metabolism

• Bioactivity :

  A8 peptide is an Hsp72 antagonist that hinders tumor progression and metastasis by disrupting the Hsp72-TLR2 interaction and subsequent activation of MDSCs, thereby increasing cancer cells' sensitivity to chemotherapeutic agents like cisplatin (Cisplatin-induced apoptosis sensitivity) . A8 peptide is applicable in cancer research.

• Smiles :

  C([C@@H](C(=O)N1[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(O)=O)=O)[C@@H](C)O)=O)CCC2)CCCNC(=N)N)=O)CCC1)NC(=O)[C@H]4N(C([C@H](CO)N)=O)CCC4)C=5C=6C(NC5)=CC=CC6

• Molecular Formula :

  C48H66N12O12

• Molecular Weight :

  1003.11

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1140483-17-5