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TpD

CAT: 0931-TP3932-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3932-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1273551-45-3
Target
MHC
Related Pathways
Immunology/Inflammation
Bioactivity
TpD is a chimeric T-helper epitope that features a specific site for cleavage by caspases. Immunization with TpD induces a strong antibody response and enhances long-term CD4 immune reactions in both animals and humans. It effectively binds to various human MHCII types, primarily HLA-DRB1, and also interacts with other HLA alleles, including DRB3, DRB4, DRB5, DP, and DQ. TpD can be utilized to amplify the immune response in peptide vaccines.
Smiles
C([C@@H](NC(CNC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CC(C)C)=O)CCSC)=O)CCC(N)=O)=O)=O)[C@H](CC)C)=O)CCCCN)=O)C)=O)CC(N)=O)=O)CO)=O)CCCCN)=O)=O)[C@H](CC)C)=O)=O)[C@H](CC)C)(=O)N3[C@H](C(N[C@H](C(NCC(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)C)=O)C(C)C)=O)CCSC)=O)CC(C)C)=O)CO)=O)CO)=O)CC(C)C)=O)C)=O)[C@H](CC)C)=O)CO)=O)CCC(N)=O)=O)CCC4)CC(C)C)=O)=O)CCSC)=O)CCC3
Molecular Formula
C158H264N38O42S3
Molecular Weight
3464.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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