TP53 neoepitope

• Target:

  MHC

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  TP53 neoepitope is a high-affinity antigen peptide that targets HLA-A and is capable of activating CD8+ T cell-mediated cytotoxicity against TP53-mutant tumor cells. It holds promise for research involving solid tumors harboring TP53 hotspot mutations (such as R175H, R273H) .

• Smiles:

  [C@@H] (CC1=CN=CN1) (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@H] (CC2=CN=CN2) N) =O) CCSC) =O) [C@@H] (C) O) =O) CCC (O) =O) =O) C (C) C) =O) [C@@H] (C) C) =O) CCCNC (=N) N) =O) C (N[C@H] (C (O) =O) CS) =O

• Molecular Formula:

  C45H74N16O13S2

• Molecular Weight:

  1111.3

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  151808-74-1