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BCY17901

CAT: 0931-TP3716-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3716-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2772542-34-2
Target
Others
Related Pathways
Others
Bioactivity
BCY17901 is a potent irreversible inhibitor of transferrin receptor 1 (TfR1) with a Ki of 12 nM. It impedes TfR1-mediated endocytosis and iron transport, thereby inhibiting the proliferation of tumor cells dependent on iron metabolism. BCY17901 is suitable for research in solid tumors such as breast cancer and glioblastoma, as well as neurodegenerative diseases.
Smiles
C([C@H](NC(=O)[C@H]1N(C([C@@H](NC(=O)[C@H]2NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](CO)NC(=O)[C@H](C(C)(C)C)NC(=O)[C@@]4(CSCC(=O)N5CN(C(=O)CSC2)CN(C5)C(=O)CSC[C@H](NC(C)=O)C(=O)N6[C@](C(=O)N7[C@@](C[C@@H](O)C7)(C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC8=CC=C(O)C=C8)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N4)[H])(CCC6)[H])[H])CCC(O)=O)=O)CCC1)C(N[C@@H](CCCCN=[N+]=[N-])C(O)=O)=O)C=9C=%10C(NC9)=CC=CC%10
Molecular Formula
C99H134N24O30S3
Molecular Weight
2236.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-P10928ABCY17901
HY-P10928BCY17901 (TFA)

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