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CT20p

CAT: 0931-TP3680-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3680-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1407967-57-0
Target
Bcl-2 Family
Related Pathways
Apoptosis
Bioactivity
CT20p is an anticancer peptide derived from the hydrophobic terminal of BaxC. It exhibits a unique cytotoxic effect independent of the full-length Bax, targeting mitochondria to induce fusion-like aggregation and mitochondrial membrane hyperpolarization. CT20p reduces α5β1 integrin levels, inhibits F-actin polymerization, thus disrupting the cytoskeleton and preventing cell adhesion. CT20p is applicable in breast cancer research.
Smiles
C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N)=O)=O)CCSC)=O)CCCCN)=O)CCCCN)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)[C@@H](C)C)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)=O)[C@H](C)C)=O)C)=O)=O)[C@@H](C)C)=O)CC(C)C)=O)[C@@H](C)O)=O)C)=O)CO)=O)CC(C)C)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)C=2C=3C(NC2)=CC=CC3
Molecular Formula
C103H170N24O25S
Molecular Weight
2176.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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CatalogName
HY-P10993CT20p

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