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NG2 binding peptide

CAT: 0931-TP3679-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TP3679-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
241478-23-9
Target
Others
Related Pathways
Others
Bioactivity
NG2 binding peptide is a specific short peptide that recognizes the NG2 proteoglycan and can be obtained via phage display technology. This peptide achieves precise targeting of tumor neovasculature in vitro and in vivo through interaction with NG2 binding sites. It demonstrates significant homing ability in wild-type tumor-bearing mice but shows no localization effect in NG2 knockout mice. Due to the tissue-specific expression of NG2, the NG2 binding peptide can be applied in tumor-targeted therapy, drug delivery, and molecular imaging diagnostics.
Smiles
[C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)C)=O)C)=O)CO)=O)=O)[C@H](C)C)=O)(C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CN=CN1)C(O)=O)=O)CCSC)=O)CO)=O)CCCNC(=N)N
Molecular Formula
C40H69N15O14S
Molecular Weight
1016.13
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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