PTD-N5-1

CAT: 0931-MF-0127225-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0127225-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2088834-68-6
Target
TLR
Related Pathways
Immunology/Inflammation
Bioactivity
PTD-N5-1 (N5-1) is an IRF5 inhibitory peptide. It can block the production of IL-12 induced by ?-glucan in both wild-type and Clec2d-deficient bone marrow-derived dendritic cells (BMDC) that are activated by IFN-?. PTD-N5-1 modulates antifungal immunity by inhibiting IRF5-mediated IL-12 production.
Smiles
C([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)C(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC4)CCCCN)=O)CCCCN)=O)=O)CCCCN)=O)CCSC)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(N)=O)=O)CCC(N)=O)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CCCCN)=O)[C@H](CC)C)=O)C=5C=6C(NC5)=CC=CC6
Molecular Formula
C148H248N52O30S
Molecular Weight
3267.95
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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