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LXY3

CAT: 0931-TP3270-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3270-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1095009-44-1
Target
Integrin
Related Pathways
Cytoskeletal Signaling
Bioactivity
LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.
Smiles
O=C1[C@]2(N(C[C@H](O)C2)C(=O)CNC(=O)[C@H](CC3=CC(N(=O)=O)=C(O)C=C3)NC(=O)CNC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](N)CSSC[C@H](C(N)=O)NC(=O)[C@H](CC(N)=O)N1)[H]
Molecular Formula
C32H43N11O15S2
Molecular Weight
885.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-P10934LXY3