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Roseltide rT1

CAT: 0931-TP3226-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP3226-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2206692-95-5
Target
Serine Protease
Related Pathways
Proteases/Proteasome
Bioactivity
Roseltide rT1 is a neutrophil elastase inhibitor (IC50=0.47 μM) and is rich in cysteine, classified as one of the Roseltides (rT1-rT8) . It has the potential to inhibit related diseases by improving neutrophil elastase-stimulated cAMP accumulation in vitro.
Smiles
O=C1N2[C@](C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)NCC(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@]3(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@]4(C(=O)N[C@@](CSSC[C@H](N)C(=O)N[C@]1([C@H](CC)C)[H])(C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N5[C@@](CCC5)(C(=O)NCC(=O)N[C@@](CSSC3)(C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)NCC(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@H](C(N[C@H](C(O)=O)C)=O)CSSC4)[H])[H])[H])[H])[H])[H])[H])[H])(CCC2)[H]
Molecular Formula
C110H177N31O31S6
Molecular Weight
2622.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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