Roseltide rT1

• Target :

  Serine Protease

• Related Pathways :

  Proteases/Proteasome

• Bioactivity :

  Roseltide rT1 is a neutrophil elastase inhibitor (IC50=0.47 ?M) and is rich in cysteine, classified as one of the Roseltides (rT1-rT8) . It has the potential to inhibit related diseases by improving neutrophil elastase-stimulated cAMP accumulation in vitro.

• Smiles :

  O=C1N2[C@](C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)NCC(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@]3(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@]4(C(=O)N[C@@](CSSC[C@H](N)C(=O)N[C@]1([C@H](CC)C)[H])(C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N5[C@@](CCC5)(C(=O)NCC(=O)N[C@@](CSSC3)(C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)NCC(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@H](C(N[C@H](C(O)=O)C)=O)CSSC4)[H])[H])[H])[H])[H])[H])[H])[H])(CCC2)[H]

• Molecular Formula :

  C110H177N31O31S6

• Molecular Weight :

  2622.16

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2206692-95-5