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VGB3

CAT: 0931-TP2984-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2984-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Apoptosis, Akt, VEGFR, mTOR, ERK, PI3K
Related Pathways
PI3K/Akt/mTOR signaling, Angiogenesis, Cytoskeletal Signaling, MAPK, Tyrosine Kinase/Adaptors, Apoptosis
Bioactivity
VGB3 is a peptide antagonist of vascular endothelial growth factor receptor 1 (VEGFR1) and VEGFR2, exhibiting anti-angiogenic and anti-tumor properties. It binds to VEGFR1 and VEGFR2, thereby inhibiting VEGF-driven endothelial cell proliferation, migration, and tube formation, as well as suppressing tumor growth and metastasis in a mouse 4T1 breast cancer model.
Molecular Formula
C67H101N19O21S2
Molecular Weight
1572.76
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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