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C5A

CAT: 0931-TP2858-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2858-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
811418-15-2
Target
HIV Protease, HCV Protease
Related Pathways
Proteases/Proteasome, Microbiology/Virology
Bioactivity
C5A is an antimicrobial peptide compound with activity against Hepatitis C Virus (HCV) and HIV. It disrupts the membrane integrity of HIV viral particles as well as the conical capsid core that encloses the viral genome. C5A inhibits in vitro infectivity of various primary HIV isolates across different primary target cells. Additionally, C5A provides protection to mice from vaginal and rectal HIV infections.
Smiles
C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC=1C=2C(NC1)=CC=CC2)NC([C@H](CO)N)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CC(O)=O)=O)[C@H](CC)C)=O)C(N[C@H](C(N[C@@H](CC=3C=4C(NC3)=CC=CC4)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CCCCN)C(O)=O)=O)=O)CC(O)=O)=O)CO)=O)CC(C)C)=O)C(C)C)=O)CCC(O)=O)=O)CS)=O)[C@H](CC)C)=O)=O)CC(O)=O)=O)C=6C=7C(NC6)=CC=CC7
Molecular Formula
C109H155N25O29S
Molecular Weight
2311.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C