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Nictide

CAT: 0931-TP2837-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2837-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1159973-22-4
Target
LRRK2
Related Pathways
Autophagy
Bioactivity
Nictide, a peptide substrate for LRRK2 (leucine-rich repeat protein kinase-2), undergoes phosphorylation by the activated form of LRRK2[G2019S], exhibiting a Km value of 10 μM.
Smiles
C([C@H](NC([C@H](CC=1C=2C(NC1)=CC=CC2)NC(CNC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CC(C)C)=O)=O)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCC(N)=O)=O)CCCCN)=O)[C@@H](C)O)=O)CC(N)=O)=O)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(C)C)=O)[C@@H](C)O)=O)=O)CC4=CC=CC=C4)=O)CCCNC(=N)N)=O)C=5C=6C(NC5)=CC=CC6
Molecular Formula
C123H193N45O28
Molecular Weight
2750.13
Shipping Conditions
Ice Packs
Storage Temperature
-20°C