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Vasculotide

CAT: 0931-TP2789-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2789-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1359657-45-6
Target
Tie-2
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
Vasculotide, an angiopoietin-1 analog, functions as a Tie-2 activator that induces Tie-2 phosphorylation. This compound exhibits anti-inflammatory properties and enhances vascular permeability. It effectively improves endothelial barrier dysfunction induced by endotoxins and promotes angiogenesis in mouse models of diabetic ulcers. Furthermore, Vasculotide protects mice from vascular leakage and reduces mortality in mouse models of abdominal sepsis. Additionally, it decreases microvascular leakage and improves microcirculation perfusion in rat models of hemorrhagic shock.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

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CRB1001060-01Vasculotide
GTR19070357-01Vasculotide TFA
CRB1001060-01Vasculotide - (Peptide)
HY-P10580A-01Vasculotide (TFA)

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