Products for Research Use Only

L57

CAT: 0931-TP2734-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2734-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2378836-93-0
Target
LDLR
Related Pathways
Metabolism
Bioactivity
L57 is a high affinity low-density lipoprotein receptor-related protein 1 (LRP1) with a Ki value of 45 nM. The compound has excellent blood-brain barrier (BBB) ​​permeability and plasma stability and can be used as a carrier for central nervous system drug delivery.
Smiles
C([C@@H](C(=O)N1[C@H](C(N[C@H](C(N[C@@H](CC2=CN=CN2)C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CN=CN4)C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CC6=CC=C(O)C=C6)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC7=CN=CN7)C(O)=O)=O)CCCCN)=O)=O)CC(C)C)=O)CCCCN)=O)CC(C)C)=O)[C@H](CC)C)=O)CO)=O)=O)=O)[C@@H](C)O)=O)=O)CCCCN)=O)CC(O)=O)=O)=O)=O)CCCCN)=O)CCC1)NC([C@H]([C@@H](C)O)N)=O)C=8C=9C(NC8)=CC=CC9
Molecular Formula
C120H175N31O27
Molecular Weight
2483.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C