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CVRARTR

CAT: 0931-TP2689-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2689-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2349354-64-7
Target
PD-1/PD-L1
Related Pathways
Apoptosis, Cell Cycle/Checkpoint, Immunology/Inflammation
Bioactivity
CVRARTR is an antagonist of programmed cell death ligand 1 (PD-L1) with a KD of 281 nM. It induces internalization of PD-L1 and decreases its levels on the cell surface. CVRARTR restores cytokine secretion and T cell proliferation in CT26 cells and demonstrates antitumor efficacy in CT26 syngeneic mouse models.
Smiles
[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)[C@@H](C)O)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CS)N)=O)C(C)C)=O)CCCNC(=N)N)=O)C)=O)CCCNC(=N)N
Molecular Formula
C33H64N16O9S
Molecular Weight
861.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19062944-01CVRARTR

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