Tiger17

CAT: 0931-TP2684-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-TP2684-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1647121-94-5

Target

TGF-beta/Smad

Related Pathways

Stem Cells

Bioactivity

Tiger17 is a potent wound healing agent that stimulates the secretion of TGF-β1 and operates via the Smad signaling pathway. It specifically enhances wound repair by increasing the phosphorylation of Smad2 and Smad3. As a polypeptide facilitating endogenous healing, Tiger17 serves as a valuable tool for studying wound healing.

Smiles

C([C@@H](C(N[C@@H]1C(=O)N[C@@H](CCCCN)C(=O)N2[C@](C(=O)N[C@@H](CCCCN)C(=O)N3C(C(=O)N[C@@H](CCCCN)C(=O)N4[C@](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(N[C@@H](CC5=CN=CN5)C(N)=O)=O)CSSC1)(CCC4)[H])(CCC3)[H])(CCC2)[H])=O)N)C=6C=7C(NC6)=CC=CC7

Molecular Formula

C62H99N21O11S2

Molecular Weight

1378.71

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Tiger17

CAS Number	1647121-94-5
PubChem CID	171714272
IUPAC Name	(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2S)-6-amino-2-[[(2R)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-3-sulfanylpropanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]-N-[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-[[(2R)-1-[[(2S)-1-amino-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-sulfanylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide
Molecular Formula	C62H99N21O11S2
Molecular Weight	1378.7
XLogP	-3.6
Topological Polar Surface Area	523
Hydrogen Bond Donor Count	18
Hydrogen Bond Acceptor Count	19
Rotatable Bond Count	40
Heavy Atom Count	96
Formal Charge	0
Complexity	2650

SMILES

C1C[C@H](N(C1)C(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)[C@H](CS)NC(=O)[C@H](CC3=CNC4=CC=CC=C43)N)C(=O)N[C@@H](CCCCN)C(=O)N5CCC[C@H]5C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC6=CN=CN6)C(=O)N

InChI

InChI=1S/C62H99N21O11S2/c63-22-6-3-15-42(75-54(87)46(33-95)79-52(85)39(66)29-36-31-72-40-14-2-1-13-38(36)40)59(92)82-27-11-20-49(82)57(90)77-44(17-5-8-24-65)61(94)83-28-12-21-50(83)58(91)76-43(16-4-7-23-64)60(93)81-26-10-19-48(81)56(89)74-41(18-9-25-71-62(68)69)53(86)80-47(34-96)55(88)78-45(51(67)84)30-37-32-70-35-73-37/h1-2,13-14,31-32,35,39,41-50,72,95-96H,3-12,15-30,33-34,63-66H2,(H2,67,84)(H,70,73)(H,74,89)(H,75,87)(H,76,91)(H,77,90)(H,78,88)(H,79,85)(H,80,86)(H4,68,69,71)/t39-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-/m0/s1

InChIKey

DWALZAYVRAWAFV-QNPIOFFVSA-N

Chemical Structure

2D Structure

CAS: 1647121-94-5

CID: 171714272

Formula: C62H99N21O11S2

MW: 1378.7

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	1378.7
XLogP3	-3.6
Hydrogen Bond Donor Count	18
Hydrogen Bond Acceptor Count	19
Rotatable Bond Count	40
Exact Mass	1377.72743541
Monoisotopic Mass	1377.72743541
Topological Polar Surface Area	523 Å²
Heavy Atom Count	96
Formal Charge	0
Complexity	2650
Isotope Atom Count	0
Defined Atom Stereocenter Count	11
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
GTR19062950-01	Tiger17
GTR19035773-01	Tiger17 TFA

Tiger17

Chemical Information

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