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PpTG20

CAT: 0931-TP2653-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2653-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
380480-75-1
Bioactivity
PpTG20 is an amphiphilic cell-penetrating peptide (KALA) utilized for gene transfection. It has the ability to bind with DNA, disrupt membrane stability, and mediate DNA transfection.
Smiles
C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N[C@H](C(O)=O)C)=O)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC(CN)=O)CC(C)C)=O)=O)CCCNC(=N)N)=O)C)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)CO)=O)CC(C)C)=O)C=2C=3C(NC2)=CC=CC3
Molecular Formula
C115H198N36O22
Molecular Weight
2437.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

H-Gly-Leu-Phe-Arg-Ala-Leu-Leu-Arg-Leu-Leu-Arg-Ser-Leu-Trp-Arg-Leu-Leu-Leu-Arg-Ala-OH
CAS Number380480-75-1
PubChem CID16214535
IUPAC Name(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-aminoacetyl)amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]propanoic acid
Molecular FormulaC115H198N36O22
Molecular Weight2437.0
XLogP1
Topological Polar Surface Area962
Hydrogen Bond Donor Count38
Hydrogen Bond Acceptor Count28
Rotatable Bond Count87
Heavy Atom Count173
Formal Charge0
Complexity5200
SMILES
C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H](CC(C)C)NC(=O)CN
InChI
InChI=1S/C115H198N36O22/c1-59(2)45-79(135-91(153)56-116)98(160)149-88(54-70-31-22-21-23-32-70)107(169)137-74(35-26-40-127-111(117)118)93(155)133-68(19)92(154)141-80(46-60(3)4)102(164)144-82(48-62(7)8)100(162)138-76(37-28-42-129-113(121)122)95(157)142-84(50-64(11)12)103(165)145-83(49-63(9)10)101(163)139-78(39-30-44-131-115(125)126)97(159)151-90(58-152)109(171)148-87(53-67(17)18)106(168)150-89(55-71-57-132-73-34-25-24-33-72(71)73)108(170)140-77(38-29-43-130-114(123)124)96(158)143-85(51-65(13)14)104(166)147-86(52-66(15)16)105(167)146-81(47-61(5)6)99(161)136-75(36-27-41-128-112(119)120)94(156)134-69(20)110(172)173/h21-25,31-34,57,59-69,74-90,132,152H,26-30,35-56,58,116H2,1-20H3,(H,133,155)(H,134,156)(H,135,153)(H,136,161)(H,137,169)(H,138,162)(H,139,163)(H,140,170)(H,141,154)(H,142,157)(H,143,158)(H,144,164)(H,145,165)(H,146,167)(H,147,166)(H,148,171)(H,149,160)(H,150,168)(H,151,159)(H,172,173)(H4,117,118,127)(H4,119,120,128)(H4,121,122,129)(H4,123,124,130)(H4,125,126,131)/t68-,69-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-/m0/s1
InChIKey
XYWKPNZZOCJJHJ-YZMIFBBKSA-N
Chemical Structure
2D Structure
2D structure of H-Gly-Leu-Phe-Arg-Ala-Leu-Leu-Arg-Leu-Leu-Arg-Ser-Leu-Trp-Arg-Leu-Leu-Leu-Arg-Ala-OH
CAS: 380480-75-1
CID: 16214535
Formula: C115H198N36O22
MW: 2437.0
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight2437.0
XLogP31
Hydrogen Bond Donor Count38
Hydrogen Bond Acceptor Count28
Rotatable Bond Count87
Exact Mass2436.5514969
Monoisotopic Mass2435.5481421
Topological Polar Surface Area962 Ų
Heavy Atom Count173
Formal Charge0
Complexity5200
Isotope Atom Count0
Defined Atom Stereocenter Count19
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-P10443PpTG20

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