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YPLP

CAT: 0931-TP2643-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2643-02Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2414391-44-7
Target
AMPK, Nrf2
Related Pathways
Chromatin/Epigenetic, Immunology/Inflammation, PI3K/Akt/mTOR signaling
Bioactivity
YPLP, a yeast-derived peptide Tyr-Pro-Leu-Pro, demonstrates anti-fatigue activity via the nuclear factor erythroid-2-related factor 2 (Nrf2) and AMP-activated protein kinase (AMPK) pathways. YPLP is orally active [1].
Smiles
C(N[C@H](C(=O)N1[C@H](C(O)=O)CCC1)CC(C)C)(=O)[C@H]2N(C([C@H](CC3=CC=C(O)C=C3)N)=O)CCC2
Molecular Formula
C25H36N4O6
Molecular Weight
488.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

H-Tyr-Pro-Leu-Pro-OH
CAS Number2414391-44-7
PubChem CID171038187
IUPAC Name(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]pyrrolidine-2-carboxylic acid
Molecular FormulaC25H36N4O6
Molecular Weight488.6
XLogP-0.9
Topological Polar Surface Area153
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count7
Rotatable Bond Count9
Heavy Atom Count35
Formal Charge0
Complexity782
SMILES
CC(C)C[C@@H](C(=O)N1CCC[C@H]1C(=O)O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC3=CC=C(C=C3)O)N
InChI
InChI=1S/C25H36N4O6/c1-15(2)13-19(24(33)29-12-4-6-21(29)25(34)35)27-22(31)20-5-3-11-28(20)23(32)18(26)14-16-7-9-17(30)10-8-16/h7-10,15,18-21,30H,3-6,11-14,26H2,1-2H3,(H,27,31)(H,34,35)/t18-,19-,20-,21-/m0/s1
InChIKey
FWNZIZLGIXKJMX-TUFLPTIASA-N
Chemical Structure
2D Structure
2D structure of H-Tyr-Pro-Leu-Pro-OH
CAS: 2414391-44-7
CID: 171038187
Formula: C25H36N4O6
MW: 488.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight488.6
XLogP3-0.9
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count7
Rotatable Bond Count9
Exact Mass488.26348488
Monoisotopic Mass488.26348488
Topological Polar Surface Area153 Ų
Heavy Atom Count35
Formal Charge0
Complexity782
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
HY-163315YPLP
MBS1036388-01Recombinant Bacillus subtilis Putative sigma L-dependent transcriptional regulator yplP (yplP)

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