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Cotransin

CAT: 0931-TP2563-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2563-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
863753-73-5
Bioactivity
Cotransin, a Sec61 translocation inhibitor, selectively prevents the stable insertion of certain nascent chains into the Sec61 translocation channel, exhibiting signal-sequence discrimination. This compound also inhibits the expression of VCAM-1 and p-selectin proteins by blocking their co-translational translocation across endoplasmic reticulum (ER) membranes (IC 50 =0.5-5 μM) . Cotransin's role extends to potential applications in inflammation and immunity research [1] [2].
Smiles
C([C@@H]1N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@@H](C)OC(=O)[C@H](C)N(C)C(=O)[C@H](CC(C)C)NC1=O)C2=CC=CC=C2
Molecular Formula
C42H68N6O8
Molecular Weight
785.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19063076-01Cotransin

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