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Apoptin-derived peptide

CAT: 0931-TP2543-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2543-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2232156-31-7
Target
Akt, Apoptosis, PI3K
Related Pathways
PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, Apoptosis
Bioactivity
Apoptin-derived peptide, an antitumor polypeptide, exhibits cytotoxic effects by promoting apoptosis and necrosis in gastric cancer (GC) cells through the modulation of the PI3K / AKT / ARNT signaling pathway. It also impedes both the invasion and migration of cancer cells by inhibiting the expression and phosphorylation of the p85 subunit of PI3K, subsequently suppressing the PI3K / AKT pathway critical to gastric cancer development [1].
Molecular Formula
C223H417N89O50S
Molecular Weight
5177.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C