Apoptin-derived peptide

• Target:

  Akt|||Apoptosis|||PI3K

• Related Pathways:

  PI3K/Akt/mTOR signaling|||Cytoskeletal Signaling|||Apoptosis

• Bioactivity:

  Apoptin-derived peptide, an antitumor polypeptide, exhibits cytotoxic effects by promoting apoptosis and necrosis in gastric cancer (GC) cells through the modulation of the PI3K / AKT / ARNT signaling pathway. It also impedes both the invasion and migration of cancer cells by inhibiting the expression and phosphorylation of the p85 subunit of PI3K, subsequently suppressing the PI3K / AKT pathway critical to gastric cancer development [1].

• Molecular Formula:

  C223H417N89O50S

• Molecular Weight:

  5177.33

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2232156-31-7