Nesiritide acetate

CAT: 0931-TP2513-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-TP2513-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1684439-46-0

Target

Others, Natriuretic peptide, Calcium Channel

Related Pathways

Membrane transporter/Ion channel, Others, GPCR/G Protein, Metabolism

Bioactivity

Nesiritide, a 32-amino acid natriuretic peptide and recombinant form of human brain natriuretic peptide, enhances vasorelaxation ex vivo in porcine hearts from an acute coronary occlusion model when given as a 2 μg/kg bolus dose followed by a 0.01 μg/kg per minute infusion, facilitated by the calcium ionophore A23187. Formulations containing nesiritide have been utilized in managing congestive heart failure.

Smiles

C(C)(O)=O.C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@@H]1C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CN=CN3)C(O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(C)C)=O)[C@@H](C)C)=O)CCCCN)=O)CSSC1)[H])=O)=O)CO)=O)=O)CCC(N)=O)=O)[C@H](C)C)=O)CCSC)=O)CCCCN)(=O)[C@H]4N(C([C@H](CO)N)=O)CCC4

Molecular Formula

C143H244N50O42S4?C2H4O2

Molecular Weight

3524.1

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-P0003A-01	Nesiritide (acetate)
GTR19062482-01	Nesiritide acetate
GTR18897406-01	Nesiritide Acetate peptide
HY-P0003-01	Nesiritide
YP-W28686-01	Mouse V Nesiritide (V Nesiritide) ELISA Kit
MBS641115-01	Vitamin A Acetate (Retinol Acetate, Retinyl Acetate)
3121815	Cupric acetate (copper acetate)
RM-L052100-01	Leuprolide Acetate (Leuprorelin Acetate)
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Nesiritide acetate

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