Laccaridione A

CAT: 0931-TN9960-01Size: 10 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-TN9960-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

320369-80-0

Target

Serine Protease

Related Pathways

Proteases/Proteasome

Bioactivity

Laccaridione A can inhibit the activity of anti-serine proteases. The IC50 values of Laccaridione A for inhibiting trypsin, papain, thermolysin, collagenase, and zinc proteases are 14.7 μg/mL, 2.5 μg/mL, 18.8 μg/mL, 7.2 μg/mL, and 18.2 μg/mL, respectively.

Smiles

OC=1C2=C(C=C3C1C(=O)C(=O)C(OC)=C3)C=C(\C(=C\C(CC)C)\C)OC2OC

Molecular Formula

C22H24O6

Molecular Weight

384.422

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Laccaridione A

Laccaridione A is an organic heterotricyclic compound that is 1H-benzo[g]isochromene-8,9-dione substituted by a hydroxy group at position 10, methoxy groups at positions 1 and 7 and a 4-methylhex-2-en-2-yl group at position 3. Isolated from the stem of the fruiting bodies of the basidiomycete strain Laccaria amethystea, it exhibits inhibitory activity against proteases. It has a role as a metabolite and a protease inhibitor. It is a member of orthoquinones, an organic heterotricyclic compound, a member of phenols, a member of isochromenes, an enol ether and a cyclic acetal.

CAS Number	320369-80-0
PubChem CID	9952015
IUPAC Name	10-hydroxy-1,7-dimethoxy-3-[(E)-4-methylhex-2-en-2-yl]-1H-benzo[g]isochromene-8,9-dione
Molecular Formula	C22H24O6
Molecular Weight	384.4
XLogP	4.8
Topological Polar Surface Area	82.1
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Heavy Atom Count	28
Formal Charge	0
Complexity	733

SMILES

CCC(C)/C=C(\C)/C1=CC2=C(C(O1)OC)C(=C3C(=C2)C=C(C(=O)C3=O)OC)O

InChI

InChI=1S/C22H24O6/c1-6-11(2)7-12(3)15-9-14-8-13-10-16(26-4)19(23)21(25)17(13)20(24)18(14)22(27-5)28-15/h7-11,22,24H,6H2,1-5H3/b12-7+

InChIKey

FBVTWLBYMYCVOT-KPKJPENVSA-N

Chemical Structure

2D Structure

CAS: 320369-80-0

CID: 9952015

Formula: C22H24O6

MW: 384.4

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	384.4
XLogP3	4.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	5
Exact Mass	384.15728848
Monoisotopic Mass	384.15728848
Topological Polar Surface Area	82.1 Å²
Heavy Atom Count	28
Formal Charge	0
Complexity	733
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	2
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
GTR19254544-01	Laccaridione A
HY-N14773	Laccaridione B

Laccaridione A

Chemical Information

Alternative Products

Popular Products