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γ-Sitosterol

CAT: 0931-TN8928-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TN8928-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
83-47-6
Target
Apoptosis|||c-Myc
Related Pathways
Cell Cycle/Checkpoint|||Apoptosis
Bioactivity
?-Sitosterol acts as an inhibitor of c-Myc. It suppresses the proliferation of cancer cells MCF-7 and A549, with IC50 values of 240.73 ?g/mL and 696.6 ?g/mL, respectively. ?-Sitosterol induces cell cycle arrest at the G2/M phase and triggers apoptosis (apoptosis) . Additionally, it upregulates the expression of cyclin B/E [cyclin B/E].
Smiles
C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CC[C@@H](C(C)C)CC)C)[H])[H]
Molecular Formula
C29H50O
Molecular Weight
414.707
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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