Taurocholic acid

CAT: 0931-TN2259-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-TN2259-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

81-24-3

Target

PI3K, TNF

Related Pathways

Apoptosis, PI3K/Akt/mTOR signaling

Purity

0.9985

Bioactivity

Taurocholic acid (N-Choloyltaurine) is a bile acid involved in fat emulsification, possessing notable biological and immunomodulatory activities. It can inhibit bile duct injury induced by hepatic artery ligation by upregulating VEGF-A expression and protect cholangiocytes from TNF-α-induced damage via a PI3K-mediated pathway, and is commonly used to induce pancreatitis models.

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[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)[C@H](C)CCC(=O)NCCS(O)(=O)=O

Molecular Formula

C26H45NO7S

Molecular Weight

515.7

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Taurocholic acid

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