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Dichotomine C

CAT: 0931-TN11459-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN11459-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
755036-45-4
Target
Interleukin, TNF, glycosidase
Related Pathways
Metabolism, Apoptosis, Immunology/Inflammation
Bioactivity
Dichotomine C ((R) - (-) -Dichotomine C) is a β-carboline alkaloid with anti-allergic properties. It inhibits the release of β-hexosaminidase from RBL-2H3 cells with an IC50 of 62 μM. Additionally, it suppresses antigen IgE-mediated release of TNF-α and IL-4 in RBL-2H3 cells, with IC50 values of 19 μM and 15 μM, respectively. This compound is applicable in the research of type I hypersensitivity reactions.
Smiles
[C@@H](CO)(O)C1=C2C(C=3C(N2)=CC=CC3)=CC(C(OC)=O)=N1
Molecular Formula
C15H14N2O4
Molecular Weight
286.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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HY-N15702Dichotomine A
HY-N15708Dichotomine C
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