NIR-BG2

• Target :

  Others|||glycosidase

• Related Pathways :

  Others|||Metabolism

• Bioactivity :

  NIR-BG2 is a near-infrared fluorescent probe that targets senescence-associated ?-galactosidase (SA-?-Gal) . Upon activation by SA-?-Gal, NIR-BG2 undergoes hydrolysis, releasing an electrophilic methylquinone that covalently binds to surrounding proteins for in situ labeling, enhancing the fluorescence signal 16-fold at 709 nm. NIR-BG2 holds potential for in vivo imaging studies of cellular senescence.

• Smiles :

  C(CC)[N+]=1C=2C(C(C)(C)C1/C=C/C3=C4C(=CC=5C(O4)=CC(OCC6=CC=C(O[C@@H]7O[C@H](CO)[C@H](O)[C@H](O)[C@H]7O)C=C6)=C(C(F)F)C5)CCC3)=CC=CC2

• Molecular Formula :

  C42H46F2NO8

• Molecular Weight :

  730.81

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3036456-18-2