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Scalaradial

CAT: 0931-TN11202-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN11202-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
53527-28-9
Target
ERK, Akt, Phospholipase, TRP/TRPV Channel
Related Pathways
Metabolism, MAPK, PI3K/Akt/mTOR signaling, Membrane transporter/Ion channel, Cytoskeletal Signaling
Bioactivity
Scalaradial is an inhibitor of bee venom phospholipase A2 (PLA2) and TRPM ion channels (TRPM2) with IC50 values of 0.07 and 0.21 μM. It regulates ERK phosphorylation by inhibiting secretory PLA2 and Akt. Additionally, Scalaradial prevents the release of Arachidonic acid in mouse peritoneal macrophages induced by PMA.
Smiles
C[C@]12[C@@]([C@]3(C)[C@@](CC1)(C(C)(C)CCC3)[H])(C[C@H](OC(C)=O)[C@@]4(C)[C@]2(CC=C(C=O)[C@@H]4C=O)[H])[H]
Molecular Formula
C27H40O4
Molecular Weight
428.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-123245Scalaradial

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