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Pestanoid A

CAT: 0931-TN11155-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN11155-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
P38 MAPK, ERK, JNK
Related Pathways
MAPK
Bioactivity
Pestanoid A is a rearranged diterpenoid that functions as an osteoclastogenesis inhibitor with an IC50 of 4.2 μM. It can be isolated from the marine-derived fungus Pestalotiopsis sp. (NBUF145) . Pestanoid A inhibits NF-kB ligand-induced activation of MAPK and NF-κB signaling pathways by preventing the phosphorylation of ERK1/2-JNK1/2-p38 MAPKs and the nuclear translocation of NF-κB. This compound may be useful in osteoporosis research.
Molecular Formula
C20H26O6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19265931-01Pestanoid A

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