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Cerberin

CAT: 0931-TN11117-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN11117-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
25633-33-4
Target
ATPase
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Cerberin is a cardiac glycoside found in C. odollam with cytotoxic and cardiac regulatory properties. It exhibits cytotoxicity against KB and NCI H187 cancer cells (IC50s = 1.92 and 1.24 μg/mL) . Cerberin inhibits Na+/K+-ATPase, elevating intracellular sodium levels and prolonging action potential duration in cardiac cells.
Smiles
O[C@@]12[C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@@H](O[C@H]5[C@@H](OC(C)=O)[C@H](OC)[C@@H](O)[C@H](C)O5)CC4)[H])(CC[C@]1(C)[C@H](CC2)C=6COC(=O)C6)[H])[H]
Molecular Formula
C32H48O9
Molecular Weight
576.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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