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Pochonin D

CAT: 0931-TN10502-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN10502-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
544712-82-5
Target
HSP, Interleukin, Virus Protease
Related Pathways
Cytoskeletal Signaling, Metabolism, Immunology/Inflammation, Microbiology/Virology
Bioactivity
Pochonin D is an inhibitor of heat shock protein 90 (Hsp90) with antiviral and anti-inflammatory properties. It disrupts Hsp90, affecting the stability, folding, and assembly of viral proteins, thereby diminishing viral replication. Additionally, Pochonin D reduces the infiltration of inflammatory cells and decreases the secretion of inflammatory cytokines such as TNF-α and IL-1β, alleviating inflammatory responses. This compound shows potential for research in human rhinovirus (HRV) infections and cancer.
Smiles
ClC1=C2C(=C(O)C=C1O)C(=O)O[C@H](C)C/C=C/CC\C=C\C(=O)C2
Molecular Formula
C18H19ClO5
Molecular Weight
350.793
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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