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Antcin B

CAT: 0931-TN10265-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-TN10265-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
163597-25-9
Target
SARS-CoV|||Virus Protease
Related Pathways
Microbiology/Virology
Bioactivity
Antcin B is an inhibitor of SARS-CoV-2 3-chymotrypsin-like protease (3CL Pro) . It interacts with several crucial amino acid residues of 3CL Pro, including Leu141, Asn142, Glu166, and His163, through hydrogen bonding, salt bridges, and hydrophobic interactions, thereby inhibiting its activity. This inhibition blocks the cleavage of viral polyproteins and suppresses the replication of the SARS-CoV-2 virus within host cells. Antcin B shows potential for research in the context of COVID-19.
Smiles
C[C@@]12C3=C([C@]4([C@](C)(CC3=O)[C@@]([C@@H](CCC(C(C(O)=O)C)=C)C)(CC4)[H])[H])C(=O)C[C@]1([C@H](C)C(=O)CC2)[H]
Molecular Formula
C29H40O5
Molecular Weight
468.625
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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