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Naphthablin

CAT: 0931-TN10164-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN10164-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
167568-51-6
Target
Bcr-Abl, DNA/RNA Synthesis
Related Pathways
Angiogenesis, Cell Cycle/Checkpoint, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, DNA Damage/DNA Repair
Bioactivity
Naphthablin is a naphthoquinone compound that inhibits the function of the Abl oncogene. It prevents the morphological transformation of v-ablts-NIH3T3 cells induced by Abl and also suppresses RNA synthesis.
Smiles
O=C1C=2[C@]3([C@@](C(C)(C)OC2C(=O)C=4C1=CC(O)=C(C(C=C)(CO)C)C4O)(C[C@H](OC(C(C)C)=O)[C@H](C)C3)[H])[H]
Molecular Formula
C29H36O8
Molecular Weight
512.591
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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