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Himachalol

CAT: 0931-TN10108-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TN10108-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1891-45-8
Target
Apoptosis, Bcl-2 Family
Related Pathways
Apoptosis
Bioactivity
Himachalol, a sesquiterpene, is an orally active compound with antispasmodic and anticancer properties found in cedarwood. It exhibits antiproliferative effects on melanoma cells and induces apoptosis (Apoptosis) by decreasing Bcl-2 levels and increasing Bax levels. Himachalol also causes systemic blood pressure reduction and peripheral vasodilation, and it inhibits carbamylcholine-induced intestinal spasms. In mice, the LD50 is 265 mg/kg (oral) and 247 mg/kg (intraperitoneal injection) .
Smiles
C[C@]1(O)[C@]2([C@](C=C(C)CC2)(C(C)(C)CCC1)[H])[H]
Molecular Formula
C15H26O
Molecular Weight
222.366
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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