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Apatinib-d8

CAT: 0931-TMID-0288-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-TMID-0288-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2468771-43-7
Target
Autophagy|||c-RET|||VEGFR|||c-Kit|||Src
Related Pathways
Apoptosis|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Autophagy
Bioactivity
Apatinib-d8 is a deuterated compound of Apatinib. Apatinib has a CAS number of 811803-05-1. Apatinib is an orally bioavailable and specific VEGFR2 inhibitor (IC50: 1 nM) . In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.
Smiles
C(#N)C1(C(C(C(C1([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])C2=CC=C(NC(=O)C3=C(NCC=4C=CN=CC4)N=CC=C3)C=C2
Molecular Formula
C24H15D8N5O
Molecular Weight
405.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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Alternative Products

CatalogName
TRC-A726153-5MGApatinib-d8
sc-480045AApatinib-d8 Hydrochloride
HY-13342SApatinib-d8 (hydrochloride)
HY-13342ASApatinib-d8 (free base)
sc-480047Apatinib-d8 25-N-Oxide Hydrochloride
HY-142440S-01Apatinib 25-N-oxide-d8 (dihydrochloride)
TRC-A726162-1MGApatinib-d8 25-N-Oxide Dihydrochloride
M16035-01Apatinib
200135Apatinib mesylate

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