21-Deoxycortisol-d8

• Target:

  Endogenous Metabolite

• Related Pathways:

  Metabolism

• Bioactivity:

  21-Deoxycortisol-d8 is a deuterated compound of 21-Deoxycortisol. 21-Deoxycortisol has a CAS number of 641-77-0. 21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11?-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies.

• Smiles:

  C[C@@]12[C@] ([C@]3 ([C@@] ([C@]4 (C) C (C (C3) ([2H]) [2H]) =C (C (=O) C (C4) ([2H]) [2H]) [2H]) ([C@@H] (O) C1) [H]) [H]) (CC[C@@]2 (C (C ([2H]) ([2H]) [2H]) =O) O) [H]

• Molecular Formula:

  C21H22D8O4

• Molecular Weight:

  354.51

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2479914-04-8