DDR1-IN-4
CAT:
804-HY-114173-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DDR1-IN-4
- CAS Number: 2125676-13-1
- UNSPSC Description: DDR1-IN-4 (Compound 2.45) is a selective and potent Discoidin Domain Receptor 1 (DDR1) autophosphorylation inhibitor, with IC50 values of 29 nM and 1.9 μM for DDR1 and DDR2, respectively[1].
- Target Antigen: Discoidin Domain Receptor
- Type: Reference compound
- Related Pathways: Protein Tyrosine Kinase/RTK
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/ddr1-in-4.html
- Purity: 98.19
- Solubility: DMSO : 250 mg/mL (ultrasonic)
- Smiles: O=C(NCC(F)(F)F)CN1C(C2(CCN(C(C3=CC=C(NN=C4)C4=N3)=O)CC2)C5=C1C=CC=C5Br)=O
- Molecular Weight: 565.34
- References & Citations: [1]Hans Richter, et al. DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome. ACS Chem Biol. 2019 Jan 18;14(1):37-49.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported