Divarasib

• Target :

  Ras|||Kras

• Related Pathways :

  MAPK|||GPCR/G Protein

• Purity :

  0.9996

• Bioactivity :

  Divarasib (GDC-6036) is an investigational, oral, high-potency and selective KRAS G12C inhibitor with an IC50 of <0.01 ?M. Divarasib irreversibly locks KRAS G12C oncoprotein in an inactive state and inhibits tumor cell growth. It is being investigated for use in solid tumors, including non-small cell lung and colorectal cancers and other types of cancer.

• Smiles :

  C[C@H]1CN(CCN1c1nc(OC[C@@H]2CCCN2C)nc2c(F)c(c(Cl)cc12)-c1nc(N)cc(C)c1C(F)(F)F)C(=O)C=C

• Molecular Formula :

  C29H32ClF4N7O2

• Molecular Weight :

  622.06

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2417987-45-0