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NC762

CAT: 0931-T9901A-947-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-947-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, TNF
Related Pathways
Others, Apoptosis
Bioactivity
NC762 is a humanized IgG1κ monoclonal antibody that targets human B7-H4 (B7 homolog 4) . Its Fc region contains three point mutations (S239D/A330L/I332E; DLE) to enhance binding to CD16a (FcγRIIIa), leading to increased antibody-dependent cellular cytotoxicity (ADCC) . By binding to tumor-expressed B7-H4, NC762 inhibits tumor growth in vivo. This compound can be utilized in research on advanced or metastatic solid tumors.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-P991223NC762
PTX25489Anti-Human VTCN1/B7-H4 (NC762)
DHJ14802Research Grade Anti-Human VTCN1/B7-H4 (NC762)
A135747Anti-VTCN1/B7-H4 (NC762) Biosimilar (Monoclonal, IgG1-kappa)

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