Products for Research Use Only

Getagozumab

CAT: 0931-T9901A-830-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-830-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2642374-04-5
Target
Endothelin Receptor
Related Pathways
GPCR/G Protein
Purity
0.989
Bioactivity
Getagozumab is a humanized IgG4-kappa monoclonal antibody that specifically targets endothelin receptor type A (EDNRA) with potent antagonistic activity. Getagozumab significantly lowered pulmonary arterial pressure in both hypoxia-induced and monocrotaline (MCT) -induced pulmonary arterial hypertension (PAH) monkey models and further attenuated the associated pulmonary arterial and right ventricular hypertrophy.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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