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Duligotuzumab

CAT: 0931-T9901A-828-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-828-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1314238-96-4
Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis
Purity
0.977
Bioactivity
Duligotuzumab is a dual-targeting human IgG1 monoclonal antibody that simultaneously binds to both epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3) . Duligotuzumab exerts its antitumor effects by blocking these dual signaling pathways and by inducing antibody-dependent cellular cytotoxicity (ADCC), targeting tumors where EGFR/HER3 overexpression correlates with poor prognosis.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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